Roman, Cameo with hand pinching an ear and a knotted scarf or...

Roman, Cameo with hand pinching an ear and a knotted scarf or diadem, 400-500 (source). The Greek inscription reads: “Remember me, your dear sweetheart, and fare well, Sophronios.” The gold setting is modern.

In Roman art and literature, the ear-tweaking hand is a common motif, signifying a request for attention. Gems such as this were mementos of love, and were probably given as gifts. The knotted object is not common, but very likely it, too, was a symbol of remembrance, its purpose similar to the modern custom of tying a know in a handkerchief so as not to forget something important. - from the Getty description